Chosen Solution

my iPhone 6s is disabled now and connect itunes, when I got to DFU mode, it is still not being detected by itunes. Not being sync at all.

It might be a due to a: bad cable, especially if it’s aftermarket.A bad charging dock, that’s the part that connects your cable to the iPhone board.A faulty logic board..if you’re trying a DFU reset, I’d think you have other issues too. You can try a different PC, an original or MFi certified cable and you can try a replacement dock. If all fails, that would point to the logic board. iPhone 6s Lightning Connector Assembly Replacement